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Abstract

To assess the effectiveness of the treatment of erectile dysfunction in Pakistan from the perspective of the patients and health care provider, a cross-sectional study was carried out with the help of a sample of the general population. The study included 90 sexually active men aged between 19 to 50 years, who were in a good quality relationship with their partners in Pakistan, having an erection that was sufficient for sexual intercourse within the previous 24 hours, and taking the drug sildenafil. The participants were randomized into three groups according to the treatment groups: the treatment group: Viagra 50mg tablet, the control group: placebo (P)

Figure 1Flow diagram of the study. The first column represents the treatment group and the third column represents the control group.

The study was carried out through a cross-sectional study. In the present study, 50% of the patients in the study were sexually active, and 50% of the patients were in a good quality relationship. It was found that there were two main groups of patients in the treatment group: Viagra 50mg tablet group and the P tablet group. The results showed that the patients in the P tablet group were more satisfied with their erectile function and with sexual intercourse within the previous 24 hours. The patients in the P tablet group were also more satisfied with their erection and with their sexual intercourse within the previous 24 hours, and they were also more satisfied with their intercourse within the previous 24 hours.

The most common side effects of Viagra were headache, flushing, nasal congestion, and indigestion. Headache and flushing were the most common side effects of P tablets, with a total of 5% and 3% of the patients in the treatment group reported headaches, and 0% and 0% of the patients in the P tablet group reported indigestion.

The results of the present study indicated that sildenafil was effective in the treatment of erectile dysfunction. The results showed that the P tablet group showed a more significant increase in the effectiveness of the medication and improved erectile function than the Viagra group. The results also showed that the patients in the P tablet group also had better overall health and sexual satisfaction. The results showed that in the P tablet group, the sexual satisfaction was better than the other groups, and the patients in the P tablet group also had better overall health and sexual satisfaction.

The study has been approved by the Institutional Review Board of Allented Drug Designation of Pakistan (ID. P. A. P.).

Figure 2Study flow diagram of the study.

Results

The results of the present study revealed that the treatment of erectile dysfunction was effective in 98% of the patients, with an increase in the effectiveness of the medication of sildenafil. There was a significant decrease in the effectiveness of Viagra. The reduction of sildenafil in the P tablet group was also significant compared to the treatment group. The results of the present study showed that the patients in the P tablet group were also more satisfied with their erectile function and with sexual intercourse within the previous 24 hours.

The results of the present study indicated that the treatment of erectile dysfunction was effective in 98% of the patients, with an increase in the effectiveness of the medication of sildenafil. The results of the present study indicated that the patients in the P tablet group also had better overall health and sexual satisfaction.

In the present study, 50% of the patients in the study were sexually active, and 50% of the patients were in a good quality relationship with their partners in Pakistan, having an erection that was sufficient for sexual intercourse within the previous 24 hours. The participants were randomized into three groups according to the treatment groups: the treatment group Viagra 50mg tablet, the control group P tablet, and the P tablet group.

Discussion

This study found that the treatment of erectile dysfunction is effective in 98% of the patients. The results showed that there was a significant increase in the effectiveness of the medication of sildenafil.

The studies carried out by the study have been performed before, and they were published in 2000s. However, they were only conducted once.

The Australian Competition and Consumer Commission (ACCC) has advised the government and the media about the growing use of sildenafil (Viagra) tablets by men and women over the age of 18.

The decision to make the drug more widely available in Australia comes a day after the government issued a letter in the wake of a growing number of reports in recent months.

“It is our view that the increasing use of Viagra tablets in the general male population will have a detrimental effect on the health of those who are affected,” the commission concluded.

The drug is the drug used to treat erectile dysfunction, which is the inability to achieve and maintain an erection during sexual activity.

The commission said that sildenafil, which is available under the brand name Viagra, had been found to be associated with an increased risk of heart attack, stroke and heart failure, with up to 15 per cent of those prescribed this medication in Australia. It also found that men who use Viagra recreationally are less likely to have heart disease or diabetes as a result.

In a statement, the government said that it was concerned that it would be the first time the use of the drug had been linked to a rare but potentially fatal condition called microvascular thrombosis.

“The association of erectile dysfunction with a rare condition called microvascular thrombosis is something that is a concern for Australian men and women who are considering taking sildenafil. We believe that sildenafil is not the only way for men and women to be protected from this potential risk,” the commission concluded.

“The increasing use of Viagra tablets in Australia will increase the risk of developing microvascular thrombosis and is something that needs to be considered carefully.”

In Australia, Viagra is sold over the counter and is used to treat erectile dysfunction in men. It is also used to treat pulmonary arterial hypertension.

The drug was originally developed to treat high blood pressure, but has been found to be less likely to increase heart disease in some people, but not all, and is not currently used by men.

The Commission said that it was concerned that Viagra would have a detrimental effect on men who use it for the purposes of erectile dysfunction.

“We are concerned that Viagra can also have a harmful effect on men who are sexually active, which is why we are now calling on the Department of Health to make this decision,” the commission concluded.

In its letter, the commission noted that the use of sildenafil in Australia is linked to an increased risk of developing microvascular thrombosis.

The commission also noted that Viagra is not approved for use in women, but is commonly sold by doctors in Australia.

“This information comes from the Australian Medicines Handbook, which is a reference to the Australian Government's website.

“We encourage people to take sildenafil if they are not sure about their condition or need to talk to a doctor. We also encourage men and women to discuss their current treatment options with their doctor, as well as any other medications they are taking, as Viagra can cause side effects, and be associated with a rare blood clot.”

Sildenafil is the only drug approved by the Australian regulatory agency to treat erectile dysfunction, but the prescription only has to be obtained by a doctor.

The commission said that sildenafil was not the only drug to be approved by the Australian regulatory agency to treat erectile dysfunction.

“The Australian Medicines Handbook has also shown the potential risks associated with the use of sildenafil in this country. This includes a number of potential adverse effects, such as an increased risk of blood clots, stroke, heart attack and other serious adverse events.”

Sildenafil is also used for the treatment of pulmonary arterial hypertension.

The commission has said that it was concerned that the increased use of Viagra tablets in Australia might have been linked to a rare condition called microvascular thrombosis.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Product variants

£29.99 (100mg) £30.99 (100mg)

  • Form:Tablets
  • Packaging:24 pack
  • Directions:Use as needed, only onuggish
  • Manufacturer:Ajanta Pharma Ltd
  • Variants:Sildenafil for pulmonary hypertension, Vitaros for pulmonary arterial hypertension, Vitaros for renal impairment, Tadarise for women, Vitaros for the treatment of pulmonary arterial hypertension, Kamagra for men, and Viagra for men.

Patient reviews

Sildenafil is a highly effective and well-tolerated medication for the treatment of ED.

Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Viagra use include:

  • Headache
  • Heartburn
  • Congestion
  • Nasal bleeding (bloody nose)
  • Nausea
  • Diarrhea
  • Muscle aches or pains
  • Flushing
  • Facial pain or tenderness
  • Vision changes
  • Light sensitivity

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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